Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Mandible / maxilla – Benign tumors / tumor-like conditions: adenomatoid odontogenic tumor.

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A case report and review of literature.

This tumor is uncommon in a patient older than 30 years. Page views in Epigenetic regulation of matrix metalloproteinase expression in ameloblastoma.

Pathology Outlines – Benign tumors / tumor-like conditions: adenomatoid odontogenic tumor

Surgical exposure of the defect Click here to view. Wide local excision is the treatment of choice. Syndecan-1 CD surface expression marks cell type and differentiation in ameloblastoma, keratocystic odontogenic tumor, and dentigerous cyst. Odontogenic Tumors and Allied Lesions.

Adenomatoid odontogenic tumor

It should be enucleated along with the associated impacted tooth and simple curettage [ 26 ]. Calcifying odontogenic cyst, odontogenic keratocyst, and giant cell granuloma were ruled out because usually they are mostly not related to the crown of an impacted tooth, and they tjmors mostly multilocular. Among 15 cases of AOT, the anterior maxilla was the most common site Adenomatoid odontogenic tumor — hamartoma or true neoplasm: In addition, the use of lyophilized bone and guided tissue regeneration are recommended in large odintogenic cavities.


The adenomatoid odontogenic tumor is an odontogenic tumor [1] arising from the enamel organ or dental lamina.

Author information Copyright and License information Disclaimer. A retrospective study of cases in a Chinese population. This page was last edited on 26 Juneat BMC Clin Pathol ; Peripheral ameloblastoma Peripheral ameloblastoma is a rare extraosseous odontogenic tumor timors histological characteristics similar to those found in conventional intraosseous ameloblastomas.

The evolution of this tumor was followed over 36 months and 24 months after excision. For the organogenesis of tooth germs, the reciprocal induction between odontogenic adeno,atoid and enamel epithelium sequentially progresses to differentiate odontoblasts into odontogenic mesenchyme and ameloblasts in the enamel epithelium.

Differential diagnosis of this image revealed a first dentigerous cyst, odontoggenic adenomatoid odontogenic tumor, and a calcifying odontogenic cyst. Indexed in Web of Science.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation

Variants of the adenomatoid odontogenic tumor with a note on tumor origin. Extra oral examination There is diffused swelling involving right anterior maxilla with moderate obliteration of nasolabial fold [ Fumors 1 ].

The significant radiological features in patients aged 30 years and above were root resorption and lesions crossing the midline. Ann Saudi Med ; The consistency was bony hard and nonfluctuant.


The prognosis is excellent in majority of the cases. Less common histologic variants are clear cell, desmoplastic, basal cell, papilliferous, and keratoameloblastoma types. The mean disease-free interval and survival for pulmonary metastasis is about Some authors still misuse the term adamantinoma to describe adenomaatoid, even though an adamantinoma, meaning “very hard,” is a rare bone tumor that differs in histology and frequency of malignancy from ameloblastomas.

Open in a separate window. With advance in the elucidation of molecular signaling mechanisms in cells, the cytodifferentiation of epithelial tumor cells in ameloblastomas and AOTs can be identified using different biomarkers.

How to cite this URL: Subscribe to Table of Contents Alerts. Kim J, Choi IJ. The tumor is well encapsulated adenomatold covered the entire crown and overlapped the root of the lateral incisor. Microscopically, the tumor is composed of spindle-shaped epithelial cells that form sheets, strands, or whorled masses of cells in a scant fibrous stroma.